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PDA risk score = (Gestation in weeks × −1.304) + (PDA diameter in mm × 0.781) + (Left ventricular output in mL/kg/min × 0.008) + (maximum PDA velocity in m/s × −1.065) + (left ventricular a' wave in cm/s × −0.470) + 41.
Score ranges between 0 (low risk) and 13 (high risk).
References:
From the Article: "The following equation was used to derive the risk score for each infant: (gestation in weeks × −1.304) + (PDA diameter in mm × 0.781) + (LVO in mL/kg/min × 0.008) + (maximum PDA velocity in m/s × −1.065) + (LV a′ wave in cm/s × −0.470) + 41, where 41 is the constant of the formula. This score ranges between 0 (low risk) and 13 (high risk). The predicted probability for each infant to develop CLD/death was also derived from the model. Infants without a PDA at the time of the scan were assigned a risk of 0 as a severity score cannot be derived from infants without a PDA diameter or maximum PDA velocity measurement."
Narrowest PDA diameter (mm) by 2D at pulmonary end
Max velocity across PDA ( in m/s);
Tissue Doppler imaging was obtained at apical 4-chamber view. Late diastolic (a′) velocities used at the level of the lateral mitral valve annulus. If the e′ and a′ waves were fused, they measured the single wave as an a′ wave.
<29 weeks: echo at 36 to 48 hours of life.
In RCT, infants with risk score of ≥5.0 deemed at high risk for chronic lung disease or death and were randomized
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