PDA score Calculator by El-Khuffash A et al.
PDA risk score = (Gestation in weeks × −1.304) + (PDA diameter in mm × 0.781) + (Left ventricular output in mL/kg/min × 0.008) + (maximum PDA velocity in m/s × −1.065) + (left ventricular a' wave in cm/s × −0.470) + 41.
Score ranges between 0 (low risk) and 13 (high risk).
References:
El-Khuffash A, James AT, Corcoran JD, Dicker P, Franklin O, Elsayed YN, Ting JY, Sehgal A, Malikiwi A, Harabor A, Soraisham AS, McNamara PJ. A Patent Ductus Arteriosus Severity Score Predicts Chronic Lung Disease or Death before Discharge. J Pediatr. 2015 Dec;167(6):1354-1361.e2. doi: 10.1016/j.jpeds.2015.09.028. Epub 2015 Oct 21. PMID: 26474706.
Narrowest PDA diameter (mm) by 2D at pulmonary end
Max velocity across PDA ( in m/s);
Tissue Doppler imaging was obtained at apical 4-chamber view. Late diastolic (a′) velocities used at the level of the lateral mitral valve annulus. If the e′ and a′ waves were fused, they measured the single wave as an a′ wave.
El-Khuffash A, Bussmann N, Breatnach CR, Smith A, Tully E, Griffin J, McCallion N, Corcoran JD, Fernandez E, Looi C, Cleary B, Franklin O, McNamara PJ. A Pilot Randomized Controlled Trial of Early Targeted Patent Ductus Arteriosus Treatment Using a Risk Based Severity Score (The PDA RCT). J Pediatr. 2021 Feb;229:127-133. doi: 10.1016/j.jpeds.2020.10.024. Epub 2020 Oct 16. PMID: 33069668.
<29 weeks: echo at 36 to 48 hours of life.
In RCT, infants with risk score of ≥5.0 deemed at high risk for chronic lung disease or death and were randomized
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